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  In this section, we evaluate effects reported for endogenous androstenedione in addition to exogenously administered in dietary dietary supplements in each sexes.
  It is value mentioning that the metabolism of androgens, in vivo, in bone could be more difficult than beneath in vitro
  situations as a end result of hormone regulation of enzyme actions [9].
  
  Androgens are circulated by way of the peripheral tissues within the body, which is adopted by immense metabolism and subsequent excretion in urine [54].
  
  Metabolism of androgen takes place mainly through hydroxysteroid dehydrogenases, reductases,
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